Studies show up to 75% of wine drinkers experience some side effects, from headaches to congestion to skin flush. The culprits? Histamines and sulfite preservatives found in both red and white wine. The symptoms of wine allergies are very similar to those experienced from common allergies to certain foods, or to pollen or pet dander. Some of us are more sensitive to these triggers because of our genetic make-up, and some of us are more sensitive due to changes in our immune systems that develop over time.